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Tramadol in the treatment of acute and chronic and pain syndrome
The basic method of the treatment of the acute and chronic pain syndromes is a systemic drug treatment in the modern medicine. It does not matter how the medication goes to the body: perorally, per rectum, sublingually, transdermally, by means of injections. It still goes to the systemic blood flow.
Now it is the problem about a choice of analgesic. They are divided into 2 groups:
Non-narcotic analgesics are prescribed for the treatment of pain of a low intensity according to the recommendations of WHO. The drugs are usually prescribed for a short period because they rather often cause side effects. They are not able to cope with severe pain syndrome.
Narcotic analgesics are prescribed to treat pain of moderate and high intensity. The drug also causes a lot of side effects, but it is impossible to imagine an effective pharmacotherapy of the pain syndrome without them.
However, there is a medication which has an efficiency of the opioid analgesics but the safety coefficient equals to the level of the non-narcotic products. This is Tramadol.
What is Tramadol?
In the context of chemistry, the drug is agonist of the opioid receptors. It is noradrenaline reuptake mediator at the same time, and it reminds the action of the antidepressants. An accumulation of noradrenaline in the central nervous system lowers the pain syndrome.
Tramadol has the double action, and so it is not worse than the opioid analgesics. But their connection is by 10 times lower than in Morphine, and therefore the index of the pharmacological safety of the drug is higher.
Due to the intensive action appearing in 20-30 minutes after the oral use (in 5-10 minutes after injection), Tramadol may be used in the treatment of the acute pain caused by the affection of the soft tissues, joints, neurological disorders, and others.
Due to rather high pharmacological safety, Tramadol may be used during chronic pain syndrome including in patients with oncology. Tramadol significantly reduces pain in patients with chronic pain associated with osteoarthritis, improves sleeping and mobility of joints, and physical functions.
Drugs on the basis of Tramadol may be prescribed for the therapy in patients with non-adequate analgesic reaction or contraindications for the use of NSAIDs or COX2 inhibitors. If a patient has diseases of the gastro-intestinal tract due to which s/he cannot take NSAIDs.
The ingredient does not cause gastro-intestinal complications typical for the NSAIDs, and does not have a potential toxicity for liver as Acetaminophen.
Tramadol does not cause a respiratory depression, cardio-vascular complications, medical addiction and has less clinic-toxicological meaning unlike opioids. That is why doctors prescribe the drug in cases when an intensive analgesic effect is required for a long period.
Doctors have a positive opinion about the use of Tramadol as the basic analgesic in the therapeutic and diagnostic practice. It has all required characteristics in order to reduce any pain syndrome. The only problem consists in the irrational use of the drug.
Most people take the drug without prescription, and it may cause an overdose and other negative symptoms.